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27.2.23

Human-Respiratory System: A complete description

 

The respiratory system is a biological system consisting of the organs and tissues responsible for gas exchange in animals and plants. In humans, the main components of the respiratory system are the nose, pharynx, larynx, trachea, bronchi, and lungs, which work together to inhale oxygen and exhale carbon dioxide. The respiratory system helps to supply oxygen to the body's cells and remove waste products, allowing to produce energy and the maintenance of life.

The respiratory system comprises of the following parts:

·         Nose: filters, warms, and moistens inhaled air

·         Pharynx: common passage for air and food

·         Larynx: houses the vocal cords, prevents food from entering the trachea

·         Trachea: conducts air to the lungs

·         Bronchi: two branches of the trachea that enter the lungs

·         Bronchioles: smaller air passages within the lungs

·         Alveoli: tiny air sacs where gas exchange occurs between air and blood.

·         Diaphragm: muscle that helps regulate breathing by changing the size of the thoracic cavity.


The physiological functions of the respiratory system can be described as follows:

·         Inhalation: The diaphragm contracts and the ribcage expand, increasing the volume of the chest cavity. This creates a pressure difference that draws air into the lungs.

·         Gas exchange: Oxygen from inhaled air diffuses into the blood vessels surrounding the alveoli, while carbon dioxide from the blood diffuses into the alveoli to be exhaled.

·         Exhalation: The diaphragm relaxes, and the ribcage decreases in size, reducing the volume of the chest cavity. This creates a pressure difference that pushes air out of the lungs.

·         Regulation of breathing: The respiratory system is regulated by a complex network of nerves and hormones that respond to changes in oxygen and carbon dioxide levels in the blood, as well as changes in physical activity and emotional state.

·    Defence mechanisms: The respiratory system also has several defence mechanisms to protect against foreign particles and microorganisms, including mucus production, cilia movement, and coughing.

The details about parts of respiratory system are as follows: -

1.      Nose

The nose plays a vital role in the respiratory system by filtering, warming, and moisturizing inhaled air. When air enters the nose, it first passes through the nostrils, which are lined with tiny hairs and mucus-secreting glands that help to filter out dust and other particles. The air then enters the nasal cavities, where it is warmed and humidified by the blood vessels in the nasal tissues. the nose can be allocated into numerous parts:

Nostrils: the external openings of the nose.

Septum: a thin wall of cartilage and bone that divides the nose into two halves.

Nasal cavity: the air-filled space inside the nose.

Olfactory mucosa: the lining in the upper part of the nasal cavity responsible for the sense of smell.

Conchae: scroll-like bones that help to increase the surface area of the nasal cavity, improving the filtration of inhaled air.

Nasal hairs: fine hairs in the nostrils that trap dust and other particles from inhaled air.

Paranasal sinuses: air-filled spaces in the bones surrounding the nasal cavity that help to reduce the weight of the skull and improve resonance of the voice.

The nose also plays a role in the sense of smell, which is important for detecting potential dangers and triggering memories and emotions.

2.      Pharynx

The pharynx, also known as the throat, is a muscular tube-like structure that serves as a common passage for both air and food. It is located in the neck, behind the nasal cavities and mouth, and extends from the base of the skull to the level of the 6th cervical vertebra.

The pharynx is divided into three regions: the nasopharynx, the oropharynx, and the laryngopharynx.

Nasopharynx: The uppermost part of the pharynx, located behind the nose. It communicates with the nasal cavities and contains the openings of the Eustachian tubes, which equalize pressure in the middle ear.

Oropharynx: The middle part of the pharynx, located behind the mouth. It is continuous with the oral cavity and contains the palatine tonsils.

Laryngopharynx: The lower part of the pharynx, located below the oropharynx and above the larynx. It is continuous with the esophagus and functions as a passage for both air and food.

The pharynx also plays a role in the production of speech by serving as a resonating chamber for the vocal cords located in the larynx. The pharynx is also involved in swallowing, which is the process of moving food from the mouth to the stomach through the esophagus.

3.      Larynx

The larynx, also known as the voice box, is a structure located in the upper part of the trachea. It is composed of several cartilages, muscles, and mucous membranes, and it serves as a critical component of the respiratory and digestive systems.

The main cartilages of the larynx include the thyroid cartilage, the cricoid cartilage, and the arytenoid cartilages. The thyroid cartilage, which forms the front part of the larynx, is commonly known as the "Adam's apple." The cricoid cartilage forms the lower part of the larynx, and the arytenoid cartilages are small triangular structures that help to move the vocal cords.

The vocal cords, or vocal folds, are two folds of mucous membrane located within the larynx. They are responsible for producing sound during speech and singing by vibrating as air passes over them.

The larynx also contains several muscles that control the position of the vocal cords and help to regulate breathing. The most important of these muscles is the cricothyroid muscle, which is responsible for changing the tension of the vocal cords and controlling the pitch of speech.

The larynx is an important structure that helps to prevent food and other foreign objects from entering the trachea and lungs. Additionally, it plays a critical role in producing speech and allowing humans to communicate with one another.

4.      Trachea

The trachea, also known as the windpipe, is a tubular structure that extends from the larynx to the bronchi in the lungs. It is approximately 10-12 cm long and 2.5 cm in diameter in adults.

The trachea is composed of several layers of tissue, including smooth muscle, connective tissue, and a mucous membrane that lines the interior of the tube. The smooth muscle in the walls of the trachea helps to regulate the diameter of the airway and control air flow.

The trachea is supported by a series of C-shaped cartilages that give it a semi-rigid structure and prevent it from collapsing. These cartilages are connected by smooth muscle and fibrous tissue and are arranged in a series of rings that encircle the trachea.

The trachea is lined with mucous membranes that produce a thin layer of mucus, which helps to trap inhaled dust, bacteria, and other foreign particles. The cilia, tiny hair-like structures on the surface of the tracheal epithelium, move in coordinated, rhythmic motions to help move mucus and trapped particles upward, towards the mouth and out of the respiratory system.

The trachea is also responsible for conducting air to the lungs. As air is breathed in through the nose or mouth, it passes through the larynx and into the trachea. From there, the air is carried to the bronchi, which branch into smaller airways called bronchioles and eventually reach the alveoli, where gas exchange between air and blood occurs.

5.      Bronchi

The bronchi are two main branches of the trachea that enter the lungs and subdivide into smaller and smaller airways, eventually forming the bronchioles, which lead to the alveoli. The bronchi are lined with mucous membranes and are supported by rings of cartilage, similar to the trachea. Like the trachea, the bronchi are composed of smooth muscle and cartilage, which help to keep the airways open and prevent them from collapsing. The bronchial walls are also lined with mucous membranes, which produce mucus that traps inhaled particles and foreign substances.

The bronchi are also responsible for regulating airflow into the lungs. During inhalation, the bronchial smooth muscle relaxes, allowing for the airways to widen and air to flow in more easily. During exhalation, the smooth muscle contracts, narrowing the airways and slowing the flow of air out of the lungs.

The bronchi play an important role in gas exchange, delivering oxygen-rich air to the alveoli and carrying carbon dioxide, a waste product, out of the lungs. The bronchial smooth muscle and cilia also help to protect the lungs from inhaled irritants and pathogens, such as dust, pollen, and bacteria.

6.      Bronchioles

Bronchioles are the small airways that branch off from the bronchi in the lungs. They are lined with smooth muscle and do not contain cartilage, which allows for greater flexibility and the ability to constrict and dilate in response to changes in airway resistance.

The bronchioles are responsible for regulating airflow and directing air to different areas of the lungs. They are divided into terminal bronchioles, which are the smallest airways that lack alveoli, and respiratory bronchioles, which contain alveoli and are involved in gas exchange.

The smooth muscle in the bronchioles can contract and relax, which affects the resistance to airflow in the lungs. This process is regulated by the autonomic nervous system, which can cause bronchoconstriction, or narrowing of the airways, in response to irritants or allergens. Bronchodilation, or widening of the airways, can also occur in response to medications or other stimuli.

7.      Alveoli

The alveoli are the small, thin-walled sacs in the lungs where gas exchange occurs between the air and the blood. The alveoli are surrounded by tiny blood vessels called capillaries, which allow for the exchange of oxygen and carbon dioxide between the air and the blood.

The walls of the alveoli are very thin, which allows for the efficient exchange of gases. The alveoli are also surrounded by a network of elastic fibres that help to maintain the shape and structure of the air sacs.

During inhalation, oxygen-rich air enters the alveoli and diffuses across the alveolar wall into the capillaries, where it binds to haemoglobin and is transported to the rest of the body. At the same time, carbon dioxide from the blood diffuses across the capillary wall and into the alveoli, where it is exhaled during exhalation.

The alveoli are also lined with a layer of fluid that helps to keep the air sacs moist and prevents them from collapsing during exhalation. This fluid is produced by cells in the alveolar wall and is regulated by a variety of factors, including hormones, nervous signals, and mechanical stress.

In addition to their role in gas exchange, the alveoli are also important for immune function. They contain a variety of immune cells, including macrophages, which help to protect the lungs from infections and other foreign substances.

8.      Diaphragm

The diaphragm is a dome-shaped, sheet-like muscle located at the base of the thoracic cavity that separates the chest from the abdominal cavity. It plays a crucial role in respiration by contracting and relaxing to change the volume and pressure within the chest cavity.

During inhalation, the diaphragm contracts and moves downward, which increases the volume of the chest cavity and creates negative pressure within the lungs. This negative pressure causes air to flow into the lungs, filling the alveoli with oxygen-rich air. During exhalation, the diaphragm relaxes and moves upward, decreasing the volume of the chest cavity and creating positive pressure that forces air out of the lungs.

The diaphragm is innervated by the phrenic nerve, which originates in the spinal cord and runs through the neck to reach the muscle. It is controlled by the respiratory centre in the brainstem, which coordinates the rhythmic contraction and relaxation of the diaphragm and other respiratory muscles.

 

In addition to its role in respiration, the diaphragm also plays a role in other bodily functions, including coughing, sneezing, and vomiting. It also helps to support the abdominal organs and maintain intra-abdominal pressure. Dysfunction of the diaphragm can lead to a variety of respiratory and gastrointestinal problems, including shortness of breath, acid reflux, and abdominal pain.